7. National & International Reputation of UK Universities for Innovation
1. Patients Now and in the Future, Urgently in Need of Cures
3. Modern scientists currently starved of public funding to develop effective human-based research methods
Mainstream development and adoption by the UK Biosciences of effective 21st Century human-based medical research technologies and techniques.
Human-based research already has a track record of success as effective 'predictive' tools for the research of human diseases and drug development. Their adoption as the gold standard, together with funded development, will undoubtedly accelerate the development of effective drugs and the discovery of cures for killer diseases and crippling conditions.
1. To inform the public that medical research scientists and clinicians openly acknowledge the use of animals (the 'animal model') is meaningless because treatments and apparent 'cures' for artificially induced diseases in animals are not effective in humans.
This is a WIN WIN for:
2. Clinical Trial Volunteers
4. Millions of Animals
5. Pharmaceutical Companies
6. UK Biosciences Economy
James Coon, CEO of Emulate
3. To inform policy makers of objective scientific evidence provided by Trans Species Modeling Theory (TSMT) which explains how and why non-human animals are NOT able to 'predict' the human response to drugs and diseases in human medical research.
4. To promote the forthcoming public scientific event, designed to lead to the updating of government policy so that it aligns with current scientific understanding on the basis of objectively testable evidence. This event is a public, properly moderated science debate between opposing scientists (organised by the science-based campaign For Life On Earth - FLOE) and called for by EDM22. The debate will be between a scientist who uses the animal model vs Dr Ray Greek MD who developed / founded Trans-Species Modeling Theory and will take place in front of a panel of impartial judges, including experts from the fields of clinical medicine, complexity/chaos theory, philosophy of science, evolutionary biology, clinical research, drug development and basic research.
'If research conducted on animals continues to be unable to reasonably predict what can be expected in humans, the public's continuing endorsement and funding of preclinical animal research seems misplaced.'
'There is a groundswell of interest across the whole industry to replace animal testing, that's driven by the lack of predictability. As we move more and more toward personalized medicine, and biologics, and things that are very human-centric.'
2. To inform the public of the non-scientific reasons that explain why animals are still claimed useful as 'predictive' for humans in medical research, despite their proven scientific invalidity.
The debate motion is 'Resolved: Animal models have no predictive value for human response to drugs and disease'. The debate will focus on claims made by the animal research community that animals are effective as 'predictive' models for humans in the research of diseases such as cancer and AIDS, and for the safety testing of drugs or other chemicals. The rigorous debate conditions, endorsed as "well set out and fair" by Britain's foremost human rights defence barrister Michael Mansfield QC, are specifically designed to achieve a scientific result which can be submitted as evidence in a wider legal action as well as to government bodies, in order to change now demonstrably outdated laws.